Download original image
When hypoalbuminemia and acute pancreatitis coexist, a degradation cycle comes into play. Intravascular proteases digest serum albumin and induce blood vessel leakage. Serum-origin proteases migrate into the interstitial space. Trypsin, in particular, serves as activator of pancreas-origin proteases, lipases and amylases. In-pancreatic activation of digestive enzymes damages pancreatic tissues and attacks vasculature from the interstitial space, allowing passage of even more destructive proteases into the serum. Systemic impacts include distribution of digestive enzymes throughout the vascular system and denial of nutrition.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.