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Table 1
Baseline endogenous intoxication, inflammatory response and tissue hypoxia, markers of prooxidant status and biochemical parameters of the antioxidant system in patients with small bowel pathology.
| Indicators | Small bowel obstruction |
Mesenteric thrombosis (n = 6) | Strangulated hernia (n = 9) | Control (n = 15) | |
|---|---|---|---|---|---|
| Obturation (n = 44) | Strangulation (n = 12) | ||||
| WBC count (×109/L) | 15.8 ± 3.63* | 21.34 ± 4.13* | 23.83 ± 4.56* | 17.32 ± 3.92* | 7.8 ± 2.1* |
| PAMW, λ = 254 нм, (c.u.) | 370 ± 12.3* | 544 ± 15.2* | 582 ± 12.7* | 422.6 ± 14.3* | 211 ± 18.1 |
| C-reactive protein (mg/L) | 93.5 ± 13.3* | 187.4 ± 28.3* | 201.5 ± 27.8* | 142.7 ± 18.6* | 6.7 ± 1.8 |
| Lactate (mmol/L) | 1.83 ± 0.12* | 3.4 ± 0.43* | 2.9 ± 0.04* | 2.2 ± 0.31* | 1.2 ± 0.03* |
| Hemoglobin (g/L) | 150.6 ± 8.09* | 156.7 ± 4.37* | 151.8 ± 9.56* | 146.4 ± 8.11* | 134.8 ± 5.4* |
| Hematocrit (%) | 43.55 ± 3.6* | 49.58 ± 4.1* | 49.24 ± 5.4* | 44.6 ± 3.9* | 34.12 ± 2.8 |
| TBA-reactive products (μM/g) | 6.78 ± 0.71* | 7.12 ± 0.66* | 7.34 ± 0.87* | 6.92 ± 0.74* | 3.58 ± 0.44 |
| DC (μM/g of protein) | 3.46 ± 0.61* | 3.85 ± 0.52* | 3.95 ± 0.44* | 3.58 ± 0.36 | 1.74 ± 0.22 |
| 8-isoprostane (ng/mL) | 4.95 ± 0.78* | 4.51 ± 0.71* | 4.59 ± 0.66* | 4.36 ± 0.68* | 2.08 ± 0.48 |
| Activity of SOD (MO/10 mg of protein) | 1.52 ± 0.21* | 0.85 ± 0.14* | 0.77 ± 0.12* | 1.05 ± 0.11* | 2.65 ± 0.12 |
| Catalase (IU/mg) | 256.1 ± 15.93* | 231.8 ± 18.02* | 223.5 ± 21.02* | 231.8 ± 18.02* | 380.3 ± 26.85 |
| GP in erythrocytes, (nmol of reduced glutathione/min) | 128.7 ± 17.86* | 112.4 ± 22.56* | 107.4 ± 17.53* | 118.4 ± 17.46* | 151.6 ± 21.24 |
WBC – white blood cells; PAMW – peptides of average molecular weight; TBA – thiobarbituric acid; SOD – superoxide dismutase; GP – glutathione peroxidase; Note: *Reliable with control (p < 0.05).