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Table 2
Laboratory data of patients in the main group depending on their severity and the presence of necrosis of the small intestine.
| Indicators | Before surgery |
P | Before surgery |
P value | |||
|---|---|---|---|---|---|---|---|
| Survivors (n = 59) | Non-survivors (n = 12) | Without necrosis small intestine (n = 44) | With necrosis small intestine (n = 27) | ||||
| WBC count (×109/L) | 17.56 ± 2.92 | 20.95 ± 4.09 | 0.007 | 16.78 ± 4.15 | 22.74 ± 5.77 | 0.000 | |
| 95% CI [−5.804 to −0.9789] | 95% CI [−8.313 to −3.607] | ||||||
| PAMW, λ = 254 нм, (c.u.) | 0.37±0.02 | 0.54±0.02 | 0.000 | 0.41±0.03 | 0.52±0.03 | 0.000 | |
| 95% CI [−0.1859 to −0.1541] | 95% CI [−0.1246 to −0.09537] | ||||||
| TBA-reactive products (μM/g) | 6.37 ± 0.71 | 7.39 ± 0.99 | 0.000 | 6.78 ± 0.71 | 7.12 ± 0.87 | 0.029 | |
| 95% CI [−1.607 to −0.4344] | 95% CI [−0.6447 to −0.03535] | ||||||
| DC (μM/g of protein) | 4.2 ± 0.26 | 3.53 ± 0.43 | 0.000 | 3.46 ± 0.61 | 3.95 ± 0.52 | 0.000 | |
| 95% CI [0.4485 to 0.8915] | 95% CI [−0.7718 to −0.2082] | ||||||
| 8-isoprostane (ng/mL) | 4.42 ± 0.52 | 4.88 ± 0.77 | 0.038 | 4.95 ± 0.78 | 4.51 ± 0.67 | 0.018 | |
| 95% CI [−0.893 to −0.02614] | 95% CI [0.07887 to −0.1541] | ||||||
| Activity of SOD (MO/10 mg of protein) | 1.59 ± 0.19 | 0.92 ± 0.16 | 0.000 | 1.52 ± 0.21 | 0.85 ± 0.14 | 0.000 | |
| 95% CI [0.521 to 0.819] | 95% CI [0.5789 to 0.7611] | ||||||
| Catalase, (IU/mg) | 268.5 ± 14.8 | 228.6 ± 19.3 | 0.000 | 256.1 ± 15.93 | 231.8 ± 18.02 | 0.000 | |
| 95% CI [27.74 to 52.06] | 95% CI [16.13 to 32.47] | ||||||
| The activity of GP in erythrocytes, nmol of reduced glutathione/min * g Hb | 126.6 ± 21.11 | 109.5 ± 18.3 | 0.043 | 128.7 ± 17.26 | 112.4 ± 22.19 | 0.000 | |
| 95% CI [0.5157 to 33.38] | 95% CI [6.904 to 25.7] | ||||||
| Lactate (mmol/L) | 1.6 ± 0.04 | 2.9 ± 0.3 | 0.000 | 1.8 ± 0.12 | 3.8 ± 0.43 | 0.000 | |
| 95% CI [−1.377 to −1.223] | 95% [CI −2.113 to −1.887] | ||||||
| C-reactive protein (mg/L) | 86.7 ± 15.8 | 193.9 ± 25.2 | 0.000 | 92.7 ± 18.6 | 198.5 ± 24.3 | 0.000 | |
| 95% CI [−120.6 to −93.84] | 95% CI [−114.1 to −97.47] | ||||||
| SBP (mm Hg) | 115.3 ± 12.9 | 88.5 ± 9.8 | 0.000 | 130.8 ± 16.4 | 81.2 ± 6.8 | 0.000 | |
| 95% CI [16.75 to 36.85] | 95% CI [42.97 to 56.23] | ||||||
| APP (mm Hg) | 75.7 ± 2.2 | 62.1 ± 1.9 | 0.000 | 70.4 ± 1.83 | 65.2 ± 1.48 | 0.000 | |
| 95% CI [11.87 to 15.33] | 95% CI [4.368 to 6.032] | ||||||
| APACHE II score | 11.3 ± 1.5 | 16.7 ± 1.4 | 0.000 | 13.7 ± 1.9 | 14.6 ± 2.09 | 0.066 | |
| 95% CI [−6.589 to −4.215] | 95% CI [−1.863 to 0.06259] | ||||||
| SOFA score | 4.3 ± 1.4 | 8.1 ± 1.2 | 0.000 | 9.3 ± 1.1 | 12.8 ± 1.3 | 0.000 | |
| 95% CI [−5.099 to −2.901] | 95% CI [−4.075 to −2.925] | ||||||
WBC – white blood cells; PAMW – peptides of average molecular weight; TBA – thiobarbituric acid; DC – diene conjugates; SOD – superoxide dismutase; GP – glutathione peroxidase; SBP – systolic blood pressure; APP – abdominal perfusion pressure; Note: P-Student’s criterion; 95% CI – 95% confidence interval for difference; APP – abdominal perfusion pressure.