Download original image
Cancer burden in regard to homeostasis and the disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm “Epistemology of the origin of cancer”. Explanation numbers: A tumor nodule is reported to be first detectable by X-ray imaging when it has 107 cells  which was earlier 108 cells . The average number of cells in a tumor when it is first palpable was reported to be 109 cells in 2002  which approximately accounts for a tumor with 1g . As it was also reported to be 106 cells in 1943 , we decided to decrease this number for the illustration by 1 log only to 108 cells.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.